diff org/ideas.org @ 141:94e03d638078

new ideas.
author Robert McIntyre <rlm@mit.edu>
date Thu, 26 Feb 2015 17:56:46 -0800
parents 208424fee6f9
children f40992b38f51
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     1.1 --- a/org/ideas.org	Thu Feb 05 23:05:45 2015 -0800
     1.2 +++ b/org/ideas.org	Thu Feb 26 17:56:46 2015 -0800
     1.3 @@ -31,6 +31,50 @@
     1.4  getting credit.
     1.5  #+end_quote
     1.6  
     1.7 +- whole brain perfusion embedding :: Do the standard EM embedding
     1.8 +     protocol, but skip the osmium step, and use the "perfusion
     1.9 +     pausing" method to prevent overextraction during the dehydration
    1.10 +     and embedding steps. I think that you CAN perfuse resins into the
    1.11 +     brain, simply because you CAN perfuse viscous rubber when doing
    1.12 +     vascular casts.
    1.13 +
    1.14 +- perfusion pausing :: One problem with doing perfusion is that if you
    1.15 +     STOP the perfusion, you rapidly loose pressure in the organ as
    1.16 +     your perfusate leaks out. You can prevent this by submerging the
    1.17 +     organ/head/rat whatever in FLUID at the appropriate level. Use
    1.18 +     something inert like flurocarbon to avoid problems. You would
    1.19 +     have to slowly decrease the flow rate while simultaneously
    1.20 +     lowering the perfusing object into the fluid. To start again,
    1.21 +     reverse the process -- reengage the peristaltic pump slowly while
    1.22 +     removing the organ from the fluid.
    1.23 +
    1.24 +- evoultionary textbook mimiricy :: as surgery becomes more common,
    1.25 +     there develops a distinct selective pressure for individuals
    1.26 +     organ layout to look more like the medical textbooks! :P
    1.27 +
    1.28 +- transparent skin :: temporary / permament transparent skin. Allows
    1.29 +     for examination of organs / muscles and visual prevention of
    1.30 +     disease and detection or abnormalities / good things
    1.31 +     eg. excercise. 
    1.32 +
    1.33 +- sweet information :: candy with a whole book written in it. Eat a
    1.34 +     book! 
    1.35 +
    1.36 +- targeted immunosuppressant :: just kill off the B-cells and friends
    1.37 +     that would cause problems in a organ-transplant / other
    1.38 +     situation. AIDS is good at killing these cells -- maybe make it
    1.39 +     just target the ones that will cause problems. Then you can
    1.40 +     premptively kill off that part of someone's immune system before
    1.41 +     a transplant. ALSO, you can kill off everyone's defenses against
    1.42 +     other blood types and make people effectively type AB+ w.r.t
    1.43 +     blood transfusions. Actually, why not give babies this treatment
    1.44 +     so that they're automatically compatable with all blood types?
    1.45 +     The immune system has this already when it's first growing; maybe
    1.46 +     it can be "retrained" to accept new things, or the mechanism of
    1.47 +     immune cell death be co-opted for these purposes.
    1.48 +
    1.49 +- fuck you tetris :: tetris that actively gives you the worst possible piece.
    1.50 +
    1.51  - pockets :: more things should have them!
    1.52  
    1.53  - colored shower head :: a shower head add on that measures the temp