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comparison org/ideas.org @ 141:94e03d638078

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new ideas.
author Robert McIntyre <rlm@mit.edu>
date Thu, 26 Feb 2015 17:56:46 -0800
parents 208424fee6f9
children f40992b38f51
comparison
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140:208424fee6f9 141:94e03d638078
28 28
29 #+begin_quote 29 #+begin_quote
30 There's no end to what a man can accomplish if he doesn't care about 30 There's no end to what a man can accomplish if he doesn't care about
31 getting credit. 31 getting credit.
32 #+end_quote 32 #+end_quote
33
34 - whole brain perfusion embedding :: Do the standard EM embedding
35 protocol, but skip the osmium step, and use the "perfusion
36 pausing" method to prevent overextraction during the dehydration
37 and embedding steps. I think that you CAN perfuse resins into the
38 brain, simply because you CAN perfuse viscous rubber when doing
39 vascular casts.
40
41 - perfusion pausing :: One problem with doing perfusion is that if you
42 STOP the perfusion, you rapidly loose pressure in the organ as
43 your perfusate leaks out. You can prevent this by submerging the
44 organ/head/rat whatever in FLUID at the appropriate level. Use
45 something inert like flurocarbon to avoid problems. You would
46 have to slowly decrease the flow rate while simultaneously
47 lowering the perfusing object into the fluid. To start again,
48 reverse the process -- reengage the peristaltic pump slowly while
49 removing the organ from the fluid.
50
51 - evoultionary textbook mimiricy :: as surgery becomes more common,
52 there develops a distinct selective pressure for individuals
53 organ layout to look more like the medical textbooks! :P
54
55 - transparent skin :: temporary / permament transparent skin. Allows
56 for examination of organs / muscles and visual prevention of
57 disease and detection or abnormalities / good things
58 eg. excercise.
59
60 - sweet information :: candy with a whole book written in it. Eat a
61 book!
62
63 - targeted immunosuppressant :: just kill off the B-cells and friends
64 that would cause problems in a organ-transplant / other
65 situation. AIDS is good at killing these cells -- maybe make it
66 just target the ones that will cause problems. Then you can
67 premptively kill off that part of someone's immune system before
68 a transplant. ALSO, you can kill off everyone's defenses against
69 other blood types and make people effectively type AB+ w.r.t
70 blood transfusions. Actually, why not give babies this treatment
71 so that they're automatically compatable with all blood types?
72 The immune system has this already when it's first growing; maybe
73 it can be "retrained" to accept new things, or the mechanism of
74 immune cell death be co-opted for these purposes.
75
76 - fuck you tetris :: tetris that actively gives you the worst possible piece.
33 77
34 - pockets :: more things should have them! 78 - pockets :: more things should have them!
35 79
36 - colored shower head :: a shower head add on that measures the temp 80 - colored shower head :: a shower head add on that measures the temp
37 of the water and changes the color of the water streams w/ an LED 81 of the water and changes the color of the water streams w/ an LED