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immunoincompatibility.
author Robert McIntyre <rlm@mit.edu>
date Fri, 24 Oct 2014 09:03:48 -0700
parents 46bc0f596b91
children 98ba603e251a
comparison
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136:46bc0f596b91 137:8bf12217d0fa
28 28
29 #+begin_quote 29 #+begin_quote
30 There's no end to what a man can accomplish if he doesn't care about 30 There's no end to what a man can accomplish if he doesn't care about
31 getting credit. 31 getting credit.
32 #+end_quote 32 #+end_quote
33
34 - immunoincompatibility :: take the human genome, and refactor it so
35 that it doesn't use a particular codon at all. Then remove the
36 support from our ribosomes for that codon. What does this do for
37 us? It makes us immune to almost all viruses!
38
39 - life cycle :: it's called a cycle, right? So, the thing that repeats
40 itself over and over, right? Not much of a cycle if
41 you don't come back after you die, if you ask me!
42
43 - car with no blind spots :: use some cameras in the back of the car
44 to augment the rear-view mirror so that you never have to turn
45 around in order to lane change.
46
47 - partial cell death :: you freeze a set of cells using some cryo
48 protocol and 60% survive. How can this be explained? It seems to
49 me that if the cells are the same, and the conditions
50 homogoneous, then all the cells should either die or
51 live. However, suppose that there is a metabolic cycle that needs
52 to be in a certain phase for the cell to survive. If the cells
53 are asynchronous, then you might end up with some cells dying
54 because there were in the wrong part of their cycle. This implies
55 that you might be able to cryoprotect cells by causing them to
56 enter a certain metabolic mode before freezing.
57
58 - cryonics color appeal :: perfusate used by cryonics companies should
59 have red food coloring in it. It's just a nice touch so that the
60 cryonics patient looks more life-like than with clear CPAs, and
61 hopefully might get treated with more respect.
62
63 - paramagnetic CPA :: you take a CPA that can be influenced by
64 magnetic fields so that its degrees of freedom are limited. Then,
65 you release the field, instantaly increasing the size of the
66 state space of the system and dramatically decreasing the
67 temperature enough to plunge the system past homogenous
68 nucleation temperature and directly to the glass transition
69 temperature, creating a doubly unstable glass at much lower CPA
70 concentrations than possible at conventional CPA concentrations.
71
72 - room temp noodles :: how does the physics of cooking noodles work?
73 Could you use a vacuum instead of heat to force water into the
74 noodle?
75
76 - personal carbon offset :: feel bad about contribuiting to global
77 warming by using electricity / driving a car? Forget trying to
78 "conserve" or "minimize your carbon footprint". Follow the
79 Platinum rule -- make the world BETTER off than you found it!
80 This would be a small, self contained system that sucks C02 out
81 of the air. It uses electricity, but it's so efficient at
82 removing CO2 that it more than offsets the CO2 produced by even a
83 coal plant to produce that electricity. This way, you can still
84 drive even a gas guzzler, but have a net negative carbon
85 footprint! Maybe something cool could be done with the carbon as
86 well. Use as much electricity as you want, but negate the damage
87 to the enviroment with more technology.
88
89 - undoing spermogenesis :: with enough sperm, you can derive the
90 donor's entire genome. You gain more confidence in the alleles
91 for a particular gene the more sperm you have. Each additional
92 sperm gives you the same sort of information you'd get flipping a
93 coin and trying to decide whether the coin is H/T of H/H. Is
94 there enough sperm in the the average load for you to be as
95 confident as mitosis?
33 96
34 - mars life :: we could engineer life that could survive on mars 97 - mars life :: we could engineer life that could survive on mars
35 (probably some non-vascular photosynthetic 98 (probably some non-vascular photosynthetic
36 poikilohydric creature like a lichen) by taking an 99 poikilohydric creature like a lichen) by taking an
37 extremophile from Antarctica and evolving it in 100 extremophile from Antarctica and evolving it in